In this talk, I will explore the transformative role of mathematical and computational modeling across diverse medical domains. Beginning with an investigation into hydrocephalus, a complex neurological condition, we will discuss how mathematical models enhance our understanding of its pathophysiology and aid in treatment optimization. Shifting focus to oncology, we examine the sequencing of therapies for cancer patients, showcasing how computational modeling facilitates improved treatment strategies to improve outcomes. Finally, we look at an emerging therapeutic modality, High-Intensity Focused Ultrasound (HIFU). We discuss the principles underlying the HIFU mechanism of action and its potential clinical applications, highlighting its promise as a non-invasive treatment option.
Professor Siv Sivaloganathan completed his Masters, PhD and Postdoctoral Fellowship at Oxford University, where he was also Senior Scholar. He held his first tenure track position at the University of Alberta, Canada (1988-1 990), but has now spent over 30 years at the University of Waterloo, Canada. He is also founding and continuing Director of the Centre for Mathematical Medicine at the Fields Institute, Toronto, Canada. Siv was Chair of the Dept of Applied Mathematics, University of Waterloo from July, 2016 until July 1
, 2023 and is currently the Axis Bank Visiting Professor at IISc, Bangalore. He is an elected Fellow of the Fields Institute, an elected Fellow of the Society for Mathematical Biology (SMB) and has been a visiting Erskine Fellow at the University of Canterbury, Christchurch, New Zealand. Amongst other accolades, Siv was awarded a University Research Chair of the University of Waterloo (2011-2018) and received the CAIMS-Fields Prize in 2023 for his contributions to Applied and Industrial Mathematics.